Bangladesh national cricket team were bowled out for 413 before Pakistan national cricket team reached 179-1 at the end of day two of the Test in Mirpur.
Pakistan still trail by 234 runs with nine wickets remaining.
Bangladesh built a strong first innings total thanks to centuries from captain Najmul Hossain Shanto, who scored 101, while Mominul Haque made 91 and Mushfiqur Rahim added 71.
Lower-order runs from Taskin Ahmed helped Bangladesh cross the 400 mark.
Pakistan pacer Mohammad Abbas claimed five wickets, while Shaheen Shah Afridi took three.
In reply, Pakistan made a steady start with opener Imam-ul-Haq scoring 45 before being dismissed by Mehidy Hasan Miraz.
Debutant Azan Awais remained unbeaten on 85 at stumps, while fellow newcomer Abdullah Fazal was not out on 37.
Bangladesh will look for early wickets on the third day to regain control of the match.
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