Despite "disappointing" recent trial results for an AstraZeneca spray, researchers suggest nasal vaccinations could still be a powerful future weapon in the fight against Covid-19.
Nasal vaccinations attempt to develop immunity in the mucous membrane that lines the nose and mouth by entering the body through the same route as the virus.
This may prevent individuals from becoming infected in the first place and may prevent those who already have Covid from spreading it further.
That would be a significant improvement over conventional shots in the arm, which have shown to be very successful for preventing severe Covid but significantly less successful at blocking transmission.
Eric Tartour, an immunologist at the European Hospital Georges Pompidou in Paris, said that while the AstraZeneca results "are indeed disappointing", he did not think the news, "dampens hope for nasal vaccines".
It was "reassuring" that the AstraZeneca, Chinese and Indian nasal vaccines have not shown any serious side effects, he added.
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